Program overview
Schematic
overview (pdf file)
Sunday September 8
 |
8h00-8h50: tutorial
courses |
|
9h00-10h45:
Cell signaling, ionic channels and receptors |
|
10h45-11h15: Poster session 1
(part 1) |
|
11h15-12h15: Electrophysiology of cochlea
and auditory pathways |
|
14h00-16h00: Development and regeneration |
|
16h-16h30: Poster session 1 (part 2) |
|
16h30-17h30: Central and peripheral
auditory morphology |
Monday September 9
Tuesday September 10
|
8h00-8h50: tutorial courses |
|
9h00-9h45: Cochlear fluids |
|
10h00-10h45: Clinical otorhinolaryngology (I) |
|
11h00-12h15: Clinical otorhinolaryngology (II) |
Detailed
program
Oral presentation abstracts
(O1-O61, large pdf file)
Poster abstracts (P1-P41, large pdf
file)
Sunday September 8
8h00-8h50: tutorial courses
|
A.F. Ryan: "Transgenic mice for inner ear
research" |
T.R. Van De Water: "Application of
experimental embryology techniques to the study of inner ear
development" |
9h00-10h45: Cell signaling,
ionic channels and receptors |
9h00 |
O1 |
Expression
patterns of tight junction membrane proteins, occludin and
claudins, in the inner ear
S.-I. Kitajiri, M. Furuse,
J. Ito & S. Tsukita |
9h15 |
O2 |
Expression
of KCNQ1-5 voltage-gated K+ channel genes in rat
and guinea pig cochleae
G. Liang, M. Ulfendahl
& L. Järlebark |
9h30 |
O3 |
Localization
of nitric oxide synthase I and iii isoforms in the microdissected
human cochlea
M. Stach, B. Schneider,
C. Schoefer, B. Pikula, P. Franz & H. Felix |
9h45 |
O4 |
Biochemical
evidence for the presence of serotonin transporters in the
rat cochlea
M.A. Vincente-Torres,
D. Dávila, M.V. Bartolomé, F. Carricondo & P. Gil-Loyzaga |
10h00 |
O5 |
Thyroid hormone
& ion channels
M. Knipper, P. Langer,
H. Winter, T. Weber, I. Köpschall, K. Rohbock & U. Zimmermann |
10h15 |
O6 |
Reversal of
vasospasms of the spiral modiolar artery (SMA): A potential
new approach for the treatment of sudden hearing loss
E. Q. Scherer, M. Herzog
& P. Wangemann |
10h30 |
O7 |
VEGF (Vascular
endothelial growth factor) dependent activation of extracellular
regulated kinase 1/2 (ERK1/2) in the cochlea of puinea pig
O. Michel, A. Hess,
D. Labbé, O. Orzechowska, M. Teranishi & W. Bloch |
10h45-11h15:
Poster session 1 (part1)
Cell signaling, ionic channels and
receptors (P1-P8) |
P1 |
Estrogen receptors
in the inner ear
Hultcrantz M, Stenberg A E, Simonoska M. |
P2 |
Expression
pattern of H3-receptor subtypes in the vestibular nuclei of
the rat
Antti A. Aarnisalo, Adrian Lozada, Kaj Karlstedt and
Pertti Panula |
P3 |
Ionic currents
of type I spiral ganglion neurones of the guinea pig
Zsolt Szabó, Csaba Harasztosi, Géza Szűcs, Zoltán Rusznák,
István Sziklai |
P4 |
An improved
procedure for the isolation of spiral ganglion cells of the
guinea pig
Csaba Harasztosi, Zsolt Szabó, Zoltán Rusznák, Géza Szűcs,
István Sziklai |
P5 |
Control of
the lateral wall stiffness by efferent neurotransmitters in
the OHCs
Tamas Jozsef Batta, Gyorgy Panyi, Istvan Sziklai |
P6 |
Arguments for
steroidogenesis in the rat cochlea
Lecain E, Guennoun R, Akwa Y., Tran Ba Huy P |
P7 |
Transcriptional
control of the cochlear motor protein
Thomas Weber, Ulrike Zimmermann, Harald Winter, Hans-Peter
Zenner, Marlies Knipper |
P8 |
Potassium channel
KCNQ4
Harald Winter, Thomas Weber, Karin Rohbock, Iris Köpschall,
Ulrike Zimmermann, Marlies Knipper |
Development and regeneration (P9-P16)
|
P9 |
Apoptotic hair cell death
after transient cochlear ischemia in gerbils
Masafumi
Taniguchi, Nobuhiro Hakuba, Kenichiro Koga, Futoshi Watanabe,
Jun Hyodo, Kiyofumi Gyo |
P10 |
Induction of neural cell
from the bone marrow cells of Chinchilla
Tatsuo
Nakamura, Seijun Fukuda, Yasuhiko Shimizu, Yasushi Naitoh |
P11 |
Epidermal growth factor
modulates the differentiation of both hair cell and support
cell immunophenotypes in rat otic epithelial clonal line 1005
high density cultures
Ken Kojima, Akiko Tanaka,
Kei Tashiro, Juichi Ito, Thomas R. Van De Water |
P12 |
p27 expression in the adult
mouse cochleae and its alteration after insults
Tsuyoshi
Endo, Takayuki Nakagawa, Tae-Soo Kim, Fukuichiro Iguchi, Ji-Eun
Lee, Norihiko Murai, Zenchi Taniguchi, Youyi Dong, Yasushi
Naito, Juichi Ito |
P13 |
Transplantation
of neural stem cells into the mouse inner ear
Fukuichiro Iguchi, Takayuki
Nakagawa, Ichiro Tateya, Tae Soo Kim, Tsuyoshi Endo, Ji Eun
Lee, Youyi Dong, Yasushi Naito, Juichi Ito |
P14 |
Ephs and ephrins in the
neonatal mouse inner ear
James
O. Pickles |
P15 |
Morphological
analysis of overproduction of hair cells and Deiters’cells
in the E19 rat organ of Corti
Marc Thiry, Brigitte
Malgrange, Philippe P. Lefevbre |
P16 |
Development of electrical
excitability in the neurons of the rat vestibular nucleus
in microexplant culture
Marlčne Genlain, Laurence
Ris, Emile Godaux |
Aging effect in the inner ear (P17-P18) |
P17 |
Suppression tuning of DPOAEs in the CBA/CaJ
mouse strain during postnatal development
MacKenzie A Howard,
Michael Syka, Karolina Uttlova, Barden B Stagner, Glen K Martin
and Brenda L Lonsbury-Martin. |
P18 |
Oxidative stress
in the aged cochlea of C57BL/6 mice
Masa-aki Teranishi,
Daniel Labbé, Wilhelm Bloch, Alexander Hess, Olaf Michel |
Central and peripheral auditory morphology (P19-P20) |
P19 |
Vasodilator-stimulated phosphoprotein in the mouse cochlea
B. Schick,
M. Praetorius, M. Eigenthaler, M. Müller, U. Walter, M. Knipper |
P20 |
Prestin-like immunoreactivity in outer hair cells of the
mustached bat (Pteronotus parnellii)
Marianne Vater, Thomas
Weber, Marlies Knipper |
11h15-12h15: Electrophysiology of cochlea and auditory
pathways |
11h15 |
O8 |
Are distortion
product otoacoustic emission (DPOAE) responses amplified,
after carboplatin treatment?
S. Hatzopoulos, J. Petruccelli
, M. Previati & A. Martini |
11h30 |
O9 |
Auditory nerve
stochasticity and deafness
S. O'Leary & R.
Shepherd |
11h45 |
O10 |
Dependence
of exocytosis at the afferent hair cell synapse on L-type
Ca2+ channels
T. Moser & A.Brandt |
12h00 |
O11 |
The consequences
of passive neural properties for eCAP recordings with the
forward-masking paradigm
T. Schrama, J. J. Briaire
& J. H.M. Frijns |
14h00-16h00: Development and regeneration |
14h00 |
O12 |
Adenovirus-mediated
GDNF prevents progressive inner hair cell loss following transient
cochlear ischemia in gerbils
N. Hakuba, M. Taniguchi,
T. Maetani, J. Hyodo, Y. Ookouchi, Y. Shimizu & K. Gyo. |
14h15 |
O13 |
Transplantation
of hair cell precursors, hair cells and stem cells in vitro
and in vivo
A. F. Ryan, K. Pak &
L. M. Mullen |
14h30 |
O14 |
Transplantation
of autologous mesenchymal stem cells into the spiral ganglion
in gentamicin-treatedchinchillas
Y. Naito, T. Nakamura,
F. Iguchi, K. Fujino, T. Endo, S. Kanemaru, T. Nakagawa, Y.
Shimizu & J. Ito |
14h45 |
O15 |
Proliferative
generation of auditory hair cells in culture
B. Malgrange, S.
Belachew,
M. Thiry, L. Nguyen, B. Rogister, M.-l. Alvarez, J.-m. Rigo,
T. R. Van De Water, G. Moonen & P. P.lefebvre |
15h00 |
O16 |
Functions of
FGFs during otic vesicle induction
Y. Alvarez, V.
Vendrell,
L. Zelarayan, M. T. Alonso & T. Schimmang |
15h15 |
O17 |
FGF signaling
regulates pillar cell development in the organ of Corti
K. L. Mueller, B. E.
Jacques & M. W. Kelley |
15h30 |
018 |
Activity-dependent
Expression of different BDNF splice variants in the cochlea
J. Tan, I. Köpschall,
K. Rohbock, U. Zimmermann & M. Knipper |
15h45 |
019 |
Molecular mechanisms
of insulin-like growth factor-1 (IGF-1) action during inner
ear development
I. Varela-Nieto &
G. Camarero |
16h-16h30: Poster session 1 (part 2)
for program, see part 1 (10h45-11h15)
16h30-17h30: Central and peripheral auditory morphology |
16h30 |
020 |
Induction of MHC class II antigens of
the inner ear
B. Gloddek, D. Bodmer, D. Brors & A. Ryan |
16h45 |
021 |
Cochlear aqueduct
flow resistance in the guinea pig, measured with small middle
ear pressure changes
H. P. Wit, R. A.
Feijen,
H. M. Segenhout & F. W. J. Albers |
17h00 |
022 |
Cochlear aqueduct flow resistance in the
guinea pig depends on (quasi) static middle ear pressure
A. Feijen, H. M. Segenhout, F. A. Albers & H. P. Wit
|
17h15 |
023 |
Deafness and
degeneration of the auditory receptor in two experimental
mouse models
M.V. Bartolomé, F.
Carricondo,
E. del Castillo, M.A. Vicente-Torres & P. Gil-Loyzaga |
17h30 |
024 |
Dose-dependant
viral vector mediated gene transfer in the cochlea of the
mouse in vivo
M. Duan, T. Bordet,
Z. Chen, M. Mezzina, A. Kahn & M. Ulfendahl |
Monday
September 9
8h00-8h50: tutorial courses
|
M.W Kelley: "Cell fate determination in
the sensory epithelium of the inner ear" |
B. Lonsbury-Martin: "Of mice, rabbits,
guinea pigs, and monkeys: Otoacoustic emission measures of
cochlear function." |
9h00-10h45: Genetic: human hereditary
deafness |
9h00 |
O25 |
Expression
of a dominant-negative connexin26 in mice causes disorganization
of organ of Corti and non-syndromic deafness
K. Ikeda,T. Kudo, S. Kure, A. Xia, Y. Katori, M. Suzuki, T. Kobayashi,
K. Kojima, Y. Suzuki, Y. Aoki & Y. Matsubara. |
9h15 |
O26 |
Degeneration
pattern of the organ of Corti of Mpv17-negative mice.
A.M. Meyer zum
Gottesberge,
H. Felix & T Massing |
9h30 |
O27 |
Otosclerosis:
a review
K. Van Den Bogaert,
C. Faghel & G. Van Camp |
9h45 |
O28 |
A combination of mouse and human studies
reveals new genes and mutations associated with auditory and
vestibular dysfunction
K.
B. Avraham, N. Ahituv, Z. Brownstein, R. Hertzano, S.
Vreugde,
T. Walsh, V. Walsh, M.-C. King, M. Hrabe de Angelis, A.
Erven,
C. Rhodes, K. P. Steel |
10h00 |
O29 |
Beethoven,
a mouse model for dominant, progressive hearing loss DFNA36
S.
Vreugde, A. Erven, C. J. Kros, W. Marcotti, H. Fuchs, K.
Kurima,
E. R. Wilcox, T. B. Friedman, A. J. Griffith, R. Balling,
M. Hrabé de Angelis, K. P. Steel & K. B. Avraham |
10h15 |
O30 |
Mutation and
expression analysis of the WFS1-gene which is a frequent cause
of autosomal dominant low frequency hearing loss
K.
Cryns, S. Thys, L. Van Laer, M. Pfister, K. Flothmann, H.
Kremer, W. Reardon, R. J.H. Smith & G. Van Camp |
10h30 |
O31 |
The DFNA5
mouse: the first analysis of the phenotype
L.
Van Laer, M. Pfister, S. Thys, L. Umans, L. Serneels, F.
Kooy,
J.-P. Timmermans, F. Van Leuven & G. Van Camp |
10h45-11h15:
Poster session 2 (part1)
Genetic: human hereditary deafness
(P21-P23) |
P21 |
Hearing
impairment related GJB2 mutations in the Hungarian population
Tímea Tóth, Susan
Kupka,
Nikolaus Blin, Hans-Peter Zenner, Markus Pfister and István
Sziklai |
P22 |
Two new otosclerosis families not linked to known loci or collagen 1
genes
Carole
Faghel, Kris Van Den Bogaert, Guy Van Camp |
P23 |
Patients affected with Fabry
disease have an increased incidence of progressive hearing
loss and sudden deafness: an investigation of 22 hemizygotes.
Pierre
Bonfils, Dominique Germain, Paul Avan |
P23
bis |
Investigating and treating progressive hearing loss associated
with lysosomal storage diseases using mouse models
Anne K. Hennig, Mark S. Sands, and Kevin K. Ohlemiller |
Otoprotection (P24-P28) |
P24 |
Reduction of acoustic trauma by systemic and local magnesium
application
Heidemarie
Haupt, Fred Scheibe, Ovidiu König |
P25 |
The effect of intracochlear drug administration against the
acoustic trauma
Hiroshi Yamashita, Kazuma Sugahara, Hiroaki Shimogori |
P26 |
Long-term effect of intracochlear administration of
betamethasone on peripheral vestibular disorder in the guinea
pig
Hiroaki Shimogori, Osamu Horiike, Takuo Ikeda, Hiroshi
Yamashita |
P27 |
Cochlear sensitivity to temporary threshold shifts is affected
by sedation/anaesthesia
Fabrice Giraudet, Kathleen Horner, Yves Cazals |
P28 |
IB1/JIP-1 peptides protect hearing and auditory hair cells
from noise and aminoglycoside-induced apoptotic death
Azel Zine, Jin Wang, Christophe Bonny, François de
Ribaupierre and Jean-Luc Puel |
Ototoxicity:
apoptosis and cell death (P29-P35) |
P29 |
Hypoxia- and
ischemia vulnerability of inner and outer hair cells
Birgit Mazurek,
Elisabeth Winter, Heidemarie Haupt, Volker Jahnke, Johann
Gross |
P30 |
Acoustic stimulation causes the expression
of inducible nitric oxide synthase (iNOS/NOS II) in the vestibule
of guinea pigs
Ken-ichi
Watanabe, Shunta Inai, Alexander Hess, Olaf Michel and Toshiaki
Yagi |
P31 |
Free radical
scavenger prevents ototoxicity after transient ischemia of
the cochlea in gerbils
Toshiki
Maetani,
Nobuhiro Hakuba, Masafumi Taniguchi, Jun Hyodo, Yoshitaka
Shimizu, Kiyofumi Gyo |
P32 |
A Mouse Model for Rapid Degeneration
of Spiral Ganglion Neuron
Tae-Soo
Kim, Takayuki Nakagawa, Ji-Eun Lee, Fukuichiro Iguchi, Tsuyoshi
Endo, Yasushi Naito, Juichi Ito |
P33 |
Time-course
of oto-vestibular toxicity from cisplatin
B. Sergi, A. Ferraresi,
D. Troiani, G:B: Azzena, G. Paludetti, M: Maurizi and A.R.
Fetoni |
P34 |
Substance
P as an antiapoptotic factor for cultured postnatal auditory
neurons
François Lallemend,
Philippe P. Lefebvre, Jean-Michel Rigo, Ingrid Breuskin, Laurent
Nguyen, Thomas R. Van De Water, Gustave Moonen & Brigitte
Malgrange |
P35 |
Local therapeutic strategy against cisplatin-induced ototoxicity in
guinea pig
Jing Wang, Ruth V. Lloyd
Faulconbridge , Ana Fetoni, Matthieu Guitton, Remy Pujol,
Jean-Luc Puel |
Cochlear fluids (P36-P38) |
P36 |
Local inner ear therapy:
A technical approach
Gerrit
Paasche, Timo Stöver, Peter Gibson, Thomas Lenarz |
P37 |
Extracellular
potassium concentration-related lateral wall stiffness in
outer hair cells
Zsolt Farkas, Tamas
J Batta, Istvan Sziklai |
P38 |
Detection
of aquaporin 2 in the epithelium of human endolymphatic sac
by immunohistochemistry
Vincent Couloigner,
Dominique Berrebi, Alexis Bozorg-Grayeli, Françoise
Cluzeaud,
Olivier Sterkers, Michel Peuchmaur, Evelyne Ferrary |
Clinical otorhinolaryngology (P39-P41) |
P39 |
A
behavioral animal model for salicylate induced Tinnitus in
rats
Lukas Rüttiger, Jürgen
Ciuffani, Hans-Peter Zenner, Marlies Knipper |
P40 |
A
behavior animal model to study the frequency characteristics
of salicylate induced Tinnitus in rats
Jürgen Ciuffani, Lukas Rüttiger, Hans-Peter Zenner, Marlies Knipper |
P41 |
Temporal bone
density measurement by CT scan in otosclerosis
A. Bozorg Grayeli, Ch.
St. Yrieix , F. Cyna-Gorse, Y. Imauchi, Pascale
Lainé, E. Ferrary, O. Sterkers |
11h15-12h15: Otoprotection |
11h15 |
O32 |
Pharmacokinetics
of caroverine in the inner ear and its effects on cochlear
function after systemic and local administrations in guinea
pigs
Z.
Chen, M. Duan, H. Lee, R. Ruan, M. Ulfendahl |
11h30 |
O33 |
Systemic a-MSH
treatment can delay ototoxicity caused by local administration
of cisplatin
F.
L.C. Wolters, S. F.L. Klis, F. P.T. Hamers, J. C.M.J. de
Groot,
D. M. Prieskorn, J. M. Miller & G. F. Smoorenburg |
11h45 |
O34 |
Are perilymphatically
administered anti-oxidants effective against cisplatin
ototoxicity?
fS. F.L. Klis, N. L.M. Cappaert, J. Wijbenga & G. F. Smoorenburg |
12h00 |
O35 |
Cell therapy
for application of neurotrophins into mouse inner ear
T.
Nakagawa, F. Iguchi, I. Tateya, T. S. Kim, T. Endo, Y. Naito
& J. Ito |
14h00 -16h00: Ototoxicity: apoptosis
and cell death (I) |
14h00 |
O36 |
Expression of hypoxia inducible
factor-1 (HIF-1) in rat cochlea
J. Gross, C. Rheinländer, J. Fuchs, B. Mazurek & T. Kietzmann |
14h15 |
O37 |
Time sequence of degeneration
pattern in the cochlea during cisplatin treatment: A quantitative
study
M. W.M. van Ruijven, J. C.M.J. de Groot & G. F.
Smoorenburg |
14h30 |
O38 |
Cisplatin
cytotoxicity in organ of Corti-derived immortalized cells
M. Previati, L. Bertolaso, D. Bindini, I. Lanzoni, E.
Corbacella, S.Hatzopoulos, S. Capitani & A. Martini |
14h45 |
O39 |
Pathomechanisms of cisplatin
and gentamicin ototoxicity
J. Lautermann, N. Dehne, U. Rauen & H. de Groot |
15h00 |
O40 |
NF-kB is a rescue pathway in
aminoglycoside-induced ototoxicity
H. Jiang, S. Sha & J. Schacht |
15h15 |
O41 |
Cochlear
effects of Hexachlorobenzene, a dioxin-type compound, in male
adult rats
S. Hadjab, D. Maurel, M. Lucciano, C. Lopez, Y. Cazals &
P. Siaud |
15h30 |
O42 |
Effects of
oxidative stress on mitochondrial function in vitro
H.
Staecker & D. Li |
15h45 |
O43 |
Aspirin Miracle Drug: It can stop your headache but can
it prevent cisplatin-induced hearing loss?
T.
Van De Water, G. Li, S.-H. Sha & J. Schacht |
16h-16h30:
Poster session 2 (part2)
for program, see part 1 (10h45-11h15)
16h30 -17h30: Ototoxicity: apoptosis
and cell death (II) |
16h30 |
O44 |
Multiple
cochlear hair cell death responses to noise
T. M. Nicotera, B. Hu
& D. Henderson |
16h45 |
O45 |
ROS
as a factor in TTS and PTS
D. Henderson, B. Hu,
E. Bielefeld & T. M. Nicotera |
17h00 |
O46 |
Extremely
rapid induction of hair cell apoptosis by impulse noise exposure
in the chinchilla cochlea
B. Hu, W. P. Yang, T.
M. Nicotera & D. Henderson |
17h30 |
O47 |
The
role of the MAPK pathway in oxidative stress-induced apoptosis
of auditory sensory cells
T. Van De Water, U.
Scarpidis, D. Mmadnani, P. Lefebvre, B. Malgrange & H.
Staecker |
Tuesday September 10
8h00-8h50: tutorial courses
|
E.W. Rubel: "Cellular and molecular
approaches towards understanding hair cell death" |
H.Staecker: "Gene therapy" |
9h00-9h45: Cochlear fluids |
9h00 |
O48 |
Endocytosis in the epithelial cells of
the endolymphatic sac
A.
Kakigi, T. Okada, T. Takeda, S. Shoichi & S. Takeuchi |
9h15 |
O49 |
Otoacoustic emissions reveal intracochlear
pressure involvement in patients with fluctuating hearing
loss and vertigo
P.
Avan, B. Büki, L. Gilain & T. Mom |
9h30 |
O50 |
The effects of V2-antagonist (OPC-31260)
on experimental endolymphatic hydrops in guinea pigs
T.
Takeda, S. Sawada, S. Takeda, H. Kitano, M. Suzuki, A. Kakigi
& S. Takeuchi |
9h45 |
O51 |
Different types of rat endolymphatic sac
mitochondria-rich cells
T.
A. Peters, E. L.G.M. Tonnaer, W.Kuijpers, C. W.R.J. Cremers
& J. H.A.J. Curfs |
10h00-10h45: Clinical otorhinolaryngology
(I) |
10h00 |
O52 |
3D-reconstruction
of the vestibular endorgans in pediatric temporal bones
E.
Bachor, T. Rother & C. Schröck-Pauli |
10h15 |
O53 |
A new concept
of tinnitus and its treatment
G.
Offutt & B. Franz |
10h30 |
O54 |
Tinitus suppression
therapy (tst) with subthreshold sound stimuli
B.
Franz & G. Offutt |
11h00-12h15: Clinical otorhinolaryngology
(II) |
11h00 |
O55 |
The
totally implantable micro drug delivery system – future implications
M. Praetorius, A. Limberger, M. Müller, B. Schick, P. Plinkert
& M. Knipper |
11h15 |
O56 |
Idiopathic
sudden sensorineural hearing loss-Will a national database
solve the mystery?
E. Hultcrantz, S. Arlinger & R. Zarenoe |
11h30 |
O57 |
Effect
of intratympanic gentamicin in vestibular function
N.
Perez & J. Rama |
11h45 |
O58 |
Fluid
dynamics of ground-based and microgravity caloric tests
M.
Kassemi & J. G. Oas |
12h00 |
O59 |
Saccular
function testing with VEMP: added value in a clinical setting?
Floris Wuyts, Mieke Hoppenbrouwers, Griet Pauwels, Paul Van de Heyning |
12h15 |
O60 |
Pharmaceutical
countermeasures for space motion sickness and the effects
on the otiliths and canals
Floris Wuyts, Griet Pauwels, Mieke Hoppenbrouwers, An Boudewyns,
Paul Van de Heyning |
12h30 |
O61 |
Unilateral otolith function testing.
Is the utricular function additive?
Floris Wuyts, Mieke Hoppenbrouwers, Griet Pauwels, Paul Van
de Heyning |
|
|
|