IEB Symposium

The Inner Ear in Translational Research

Closing the gap toward causal treatment

29. September 2012

I. Endogene causes of hearing loss

Dirk Kunst, University Medical Centre St. Radboud, Nijmegen, The Netherlands
Genotype-phenotype correlations in non-syndromic hearing loss

Hannie Kremer, University Medical Centre St. Radboud, Nijmegen, The Netherlands
Causative genes involved in nonsyndromic sensorineural hearing loss

Saskia Biskup, CeGaT GmbH, Tübingen, Germany
Next-generation sequencing for genome-wide genotyping allowing for diagnosis of new deafness genes

II. Exogene causes of hearing loss

Edwin Rubel, Washington University, Seattle, USA
Drug development through in vivo high-throughput screening: Genetic and pharmacological modulation of hair cell toxicity

Jonathan Gale, University College London Ear Institute, London, UK
Sensory hair cell death and protection

III. Screening and stem cell technologies

Marcelo N. Rivolta, University of Sheffield, Sheffield, UK
Stem cells for potential future treatment options for hearing disorders

Albert Edge, Harvard Medical School, Boston, USA
Cell-based assays using screening technologies in the search for new drugs

IV. Drug delivery to the inner ear

Alec N. Salt, Washington University School of Medicine, St. Louis, USA
Manipulations of the cochlea and measurement of functional status

Takayuki Nakagawa, Kyoto University, Kyoto, Japan
Intracochlear drug delivery systems and new therapeutic concepts